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This Concept Map, created with IHMC CmapTools, has information related to: Cholesterol Synthesis, Cholelithiasis: leads to gallstones defiencicy of Primary and Secondary Bile Salts (liver), Cholesterol 7 Alpha Hydroxylase converts Cholesterol, phosphoprotein phosphatase converts HMG CoA Reductase (inactive), Cholesterol inhibits LDL Receptors, Sterols promote degradation of HMG CoA Reductase (active), Primary Bile Acids (liver) into Primary and Secondary Bile Salts (liver), Cholesterol inhibits SREBP-SCAP, SREBP-SCAP promotes transcription of HMG CoA Reductase (active), Secondary Bile Acids (liver via portal vein) converted to Primary and Secondary Bile Salts (liver), Primary and Secondary Bile Salts (liver) excreted into Duodenum (via bile duct), Secondary Bile Acids (duodenum) into Secondary Bile Acids (liver via portal vein), Insulin promotes transcription of HMG CoA Reductase (active), Mecalonate into Cholesterol, Cholesterol into Primary Bile Acids (liver), Duodenum (via bile duct) into Secondary Bile Acids (duodenum), HMG CoA Reductase (inactive) into HMG CoA Reductase (active), HMG CoA Reductase (active) converts Mecalonate